+The function
+@code{message-send-mail-with-sendmail} pipes your article to the
+@code{sendmail} binary for further queuing and sending. When your local
+system is not configured for sending mail using @code{sendmail}, and you
+have access to a remote @acronym{SMTP} server, you can set
+@code{message-send-mail-function} to @code{smtpmail-send-it} and make
+sure to setup the @code{smtpmail} package correctly. An example:
+
+@lisp
+(setq message-send-mail-function 'smtpmail-send-it
+ smtpmail-default-smtp-server "YOUR SMTP HOST")
+@end lisp
+
+To the thing similar to this, there is
+@code{message-smtpmail-send-it}. It is useful if your @acronym{ISP}
+requires the @acronym{POP}-before-@acronym{SMTP} authentication.
+@xref{POP before SMTP, , POP before SMTP, gnus, The Gnus Manual}.
+